Recent Publications that Cite Crystal Chem Kits

Melena, I., et al. “Primary cilia regulate GLP-1 signaling in pancreatic β cells.” Molecular Metabolism 2026. Read more ›

Tzeng, J., et al. “Maternal BCAA overnutrition programs persistent dysglycemia in lean adult offspring.” Molecular Metabolism 2026. Read more ›

Jung, S., et al. “Efficacy of Photothermal Duodenal Mucosal Ablation (PDMA) on Glycemic Control in a Type 2 Diabetic Rat Model.” Applied Sciences 2026; 16(4): 1788. Read more ›

Abdelhameed, A. M., et al. “Adiponectin Receptor Agonist AdipoRon Ameliorates the Metabolic Complications in a Hyperandrogenic Rat Model of PCOS.” Endocrinology 2026; 167(1): bqaf173. Read more ›

Chinnarasu, S., et al. “Hepatic Cholesteryl Ester Transfer Protein Regulates Sex-specific Liver Metabolic Adaptation and Metabolic-Associated Steatotic Liver Disease Risk in Diet-induced Obesity.” bioRxiv 2026. Read more ›

Liu, X., et al. “Hepatic glutathione depletion ameliorates MASLD through selective protein oxidation and inhibition of lipogenesis.” J Clin Invest. 2026; 136(8). Read more ›

Liskiewicz, D., et al. “GLP-1R–GIPR–PPARα/γ/δ quintuple agonism corrects obesity and diabetes in mice.” Nature 2026. Read more ›

Walth-Hummel, A. A., et al. “TBL1X/TBL1XR1 govern β-cell identity through a PAX6-containing gene regulatory network.” Nature Communications 2026. Read more ›

Heyward, F. D., et al. “Evidence of persistent hunger following dietary weight loss in mice.” iScience 2026; 29(4): 115248. Read more ›

Hossain, S., et al. “Gpr75 Deletion in Adipocytes Protects From Diet-Induced Obesity: Changes in Glucose Homeostasis and Inflammatory Responses.” The FASEB Journal 2026; 40(4): e71579. Read more ›

Knopf, B. A., et al. “Female resistance to the metabolic benefits of protein restriction is reversed by ovariectomy in mice.” bioRxiv 2026. Read more ›

Velingkaar, N., et al. “Anticipatory metabolic reprogramming distinguishes caloric restriction from fasting-refeeding cycles.” bioRxiv 2026. Read more ›

Gray, L., et al. “Aged Male Mice Remain Glucose Tolerant Despite Increased Energy Storage Efficiency Favoring Diet-Induced Obesity.” Aging Cell 2026; 25(3): e70441. Read more ›

Zalucha, E. M., et al. “The Role of Pancreatic Preproglucagon in Regulating Local Inflammation in Mice.” Cells 2026; 15(5): 482. Read more ›

Palikhe, S., et al. “Brca1 heterozygosity leads to hepatic steatosis in male and female mice despite sexually dimorphic effects on systemic metabolism.” bioRxiv 2026. Read more ›

Lin, Y., et al. “Pharmacological administration of FGF21 reverses obesity through a parabrachial-projecting neuron population in the hindbrain.” Cell Reports 2026; 45(4): 117093. Read more ›

Bruzina, A. S., et al. “Novel assessment of postprandial metabolism reveals sex-specific metabolic flexibility and lipid remodeling following volumetric muscle loss.” American Journal of Physiology – Regulatory, Integrative and Comparative Physiology 2026; 330(2): R243–R260. Read more ›

Wu, H., et al. “Transplantation of Soluble Epoxide Hydrolase Inhibitor-Treated Human Brown Adipocytes Promotes Adipose Tissue Activation in High-Fat-Diet-Fed Nude Mice.” International Journal of Molecular Sciences 2026; 27(3): 1440. Read more ›

Abdollahi, M., et al. “Metabolic beneficial effects of targeting a long non-coding RNA, lnc-megacluster, in obesity.” Molecular Therapy Nucleic Acids 2026. Read more ›

Burton, J. J. N., et al. “Sex-Dependent Diabetes Impact of Acute Grp78 Deletion in β-Cells of Adult Mice.” Diabetes 2026. Read more ›

Chang, R. C., et al. “Heritable changes in chromatin contacts associated with transgenerational susceptibility to diet-induced insulin dysregulation and obesity.” Nature Communications 2026; 17: 2662. Read more ›

Chini, J., et al. “CD9 regulates macrophage-mediated remodeling of adipose tissue in obesity.” JCI Insight 2026; e193837. Read more ›

Doncheva, A. I., et al. “Elevated adipose inflammation, but reduced hepatic triacylglycerol storage in diet-induced obese Plin4−/− mice.” Journal of Biological Chemistry 2026. Read more ›

Duan, S., et al. “Hedgehog signaling drives glial cell plasticity and oncogenic reprogramming in gastroenteropancreatic neuroendocrine neoplasms.” Molecular Cancer 2026; 25: 85. Read more ›

Huang, L., et al. “Adissp activates insulin-independent glucose disposal and energy expenditure in white fat to treat diabetes and cardiometabolic disease.” Science Advances 2026; 10.1126/sciadv.aed2780. Read more ›

Lee, D., et al. “Beta-cell adaptation to metabolic stresses requires prolactin receptor signaling.” American Journal of Physiology – Endocrinology and Metabolism 2026. Read more ›

Li, H., et al. “Elevated MANF expression in β cells protects mice from streptozotocin-induced diabetes by attenuating islet stress and immunogenicity.” Molecular Therapy 2026. Read more ›

Li, L., et al. “Deficiency of glycogen synthase promotes lipid accumulation through ChREBP and AKT-mTOR1-SREBP1 axis activation in mice.” Journal of Lipid Research 2026. Read more ›

Li, X., et al. “Multi-omics Insights into the Mitigation of Diet-induced Obesity by Dendrobium officinale Polysaccharides via Gut-Adipose Tissue Axis Modulation of Lipid Droplets.” Food Science and Human Wellness 2026. Read more ›

Lu, W., et al. “Gardenia jasminoides Ellis polysaccharides improve gut microbiota disorder and glucose homeostasis in type 2 diabetic mice.” Fitoterapia 2026. Read more ›

Merrild, C., et al. “Sex-specific metabolic responses to glucagon receptor agonism and modulation of the FGF21-glucagon axis in female mice.” The Journal of Physiology 2026. Read more ›

Nan, J., et al. “Single-cell perturbations decipher ribosomal stress-surveillance regulators in type 2 diabetes.” Nature Metabolism 2026; 8: 139–158. Read more ›

Niu, Y., et al. “Lactate-activated GPR81/FARP1 signaling drives insulin-independent glucose uptake and metabolic control.” Cell Research 2026. Read more ›

Norambuena-Soto, I., et al. “Angiotensin-(1–9) attenuates diabetic cardiomyopathy by improving insulin resistance.” British Journal of Pharmacology 2026. Read more ›

Patel, S., et al. “Loss of Beta-Cell Identity and Function as a Mechanism of Secondary Failure of Sulfonylurea Therapy in Diabetes.” MedComm 2026. Read more ›

Qiao, Y., et al. “Clinical and functional characteristics of the KLF11 (p. R29Q) variant associated with MODY7.” Frontiers in Endocrinology 2026. Read more ›

Xu, H., et al. “DNA2 acts as a brake on β cell insulin hypersecretion and diet-induced metabolic dysfunction.” Frontiers in Cell and Developmental Biology 2026. Read more ›

Yang, Y., et al. “Glucagon-like peptide-1 receptor agonists ameliorate polycystic ovarian syndrome in mice by regulating the irisin level and activating the BMP4-Smad signaling pathway.” Biology of Reproduction 2026. Read more ›

Zhang, Z., et al. “Macronutrient Composition and Genetic Background Determine the Response to a Ketogenic Diet.” bioRxiv 2026. Read more ›

Inal, S., et al. “Plasma Metabolomic Profiling Reveals Systemic Alterations in a Mouse Model of Type 2 Diabetes.” Metabolites 2025; 15(9): 564. Read more ›

Coassolo, L., et al. “Prohormone cleavage prediction uncovers a non-incretin anti-obesity peptide.” Nature 2025; 641(8061): 192–201. Read more ›

Kong, B. S., et al. “The mitochondrial NAD transporter SLC25A51 is a modulator of beta cell senescence and type 2 diabetes.” bioRxiv 2025; 10.1101/2025.04.09.647991. Read more ›

Waite, E. L., et al. “The IsletTester Mouse: An Immunodeficient Model With Stable Hyperglycemia for the Study of Human Islets.” Diabetes 2025; 74(3): 332. Read more ›

Algenabi, S. M. H., et al. “Decoding the association of polycystic ovary syndrome with metabolic-associated fatty liver: insights into CK18 and LC3II/ATG7/P62 autophagy axis and adjunct therapeutics of metformin and levothyroxine.” RSC Medicinal Chemistry 2026. Read more ›

Banah, A. K., et al. “Eplerenone improves kidney function and cardiac performance in obese male mice.” Diabetic Medicine 2026. Read more ›

Rahmani, M., et al. “Type 2 Diabetes disrupts T-tubule and RyR2 organisation in male but not female rat ventricular muscle.” American Journal of Physiology – Heart and Circulatory Physiology 2026. Read more ›

Zhu, C., et al. “The Mechanism Study of the Yi-Zhi-Fang-Dai Formula in Protecting Against Cognitive Dysfunction in Diabetic Rats via Mediating Brain Endothelial Cell Pyroptosis.” Modernization of Traditional Chinese Medicine and Materia Medica 2026. Read more ›

Liu, X., et al. “Hepatic glutathione depletion ameliorates MASLD through selective protein oxidation and inhibition of lipogenesis.” J Clin Invest. 2026; 136(8). Read more ›

Carlein, C., et al. “Adaptive mechanisms in pancreatic islets counteract mitochondrial dysfunction in Barth syndrome.” Diabetologia 2026; 69: 173–197. Read more ›

Jin, E., et al. “Amino Acid Sensing by the α-Cell Mitochondrial Phosphoenolpyruvate Cycle Regulates Intracellular Ca²⁺ Levels Without Affecting Glucagon Secretion.” Diabetes 2026; 10.2337/db25-0510. Read more ›

Duan, S., et al. “Hedgehog signaling drives glial cell plasticity and oncogenic reprogramming in gastroenteropancreatic neuroendocrine neoplasms.” Molecular Cancer 2026; 25: 85. Read more ›

El Eid, L., et al. “In vivo functional profiling and structural characterization of the human GLP1R A316T variant.” Science Advances 2026. Read more ›

Huang, L., et al. “Adissp activates insulin-independent glucose disposal and energy expenditure in white fat to treat diabetes and cardiometabolic disease.” Science Advances 2026; 10.1126/sciadv.aed2780. Read more ›

Patel, S., et al. “Loss of Beta-Cell Identity and Function as a Mechanism of Secondary Failure of Sulfonylurea Therapy in Diabetes.” MedComm 2026. Read more ›

Zhang, Z., et al. “Macronutrient Composition and Genetic Background Determine the Response to a Ketogenic Diet.” bioRxiv 2026. Read more ›

Zhou, Y., et al. “Hepatic GAPDH prevents excessive fasting-induced steatosis via serine-dependent inhibition of diacylglycerol synthesis.” Cell Death & Differentiation 2026. Read more ›

Coassolo, L., et al. “Prohormone cleavage prediction uncovers a non-incretin anti-obesity peptide.” Nature 2025; 641(8061): 192–201. Read more ›

Ayachi, C., et al. “Harnessing Gut Endocrine Cell Plasticity to Restore Insulin Production.” Cells 2026; 15(6): 544. Read more ›

Duan, S., et al. “Hedgehog signaling drives glial cell plasticity and oncogenic reprogramming in gastroenteropancreatic neuroendocrine neoplasms.” Molecular Cancer 2026; 25: 85. Read more ›

Lee, E., et al. “Effects of Daily Saskatoon Berry Supplementation on Cardiometabolic Health, Gut Microbiota, and Short-Chain Fatty Acids in Healthy Adults.” International Journal of Molecular Sciences 2026. Read more ›

Liu, R., et al. “Multi-Omics Revealed the Effects of Intrauterine Hyperglycemia Exposure on the Development of Skeletal Muscle in Offspring.” Journal of Cachexia, Sarcopenia and Muscle 2026. Read more ›

Melena, I., et al. “Primary cilia regulate GLP-1 signaling in pancreatic β cells.” Molecular Metabolism 2026. Read more ›

Ugidos, I. F., et al. “Transient neurovascular coupling impairment in brain penetrating arterioles of streptozotocin treated mice post recurrent nonsevere hypoglycemia.” iScience 2026. Read more ›

Gray, L., et al. “Aged Male Mice Remain Glucose Tolerant Despite Increased Energy Storage Efficiency Favoring Diet-Induced Obesity.” Aging Cell 2026; 25(3): e70441. Read more ›

McFadden, S. A., et al. “Surgical removal of visceral adipose tissue has therapeutic benefit in male APP^NL-F mice.” Frontiers in Endocrinology 2026. Read more ›

Abdelhameed, A. M., et al. “Adiponectin Receptor Agonist AdipoRon Ameliorates the Metabolic Complications in a Hyperandrogenic Rat Model of PCOS.” Endocrinology 2026; 167(1): bqaf173. Read more ›

Gray, L., et al. “Aged Male Mice Remain Glucose Tolerant Despite Increased Energy Storage Efficiency Favoring Diet-Induced Obesity.” Aging Cell 2026; 25(3): e70441. Read more ›

Chang, R. C., et al. “Heritable changes in chromatin contacts associated with transgenerational susceptibility to diet-induced insulin dysregulation and obesity.” Nature Communications 2026; 17: 2662. Read more ›

Jo, S., et al. “Prevention of Weight Regain After GLP1RA Cessation With Oral TIX100.” Diabetes, Obesity and Metabolism 2026; 28(6): 5339–5342. Read more ›

McFadden, S. A., et al. “Surgical removal of visceral adipose tissue has therapeutic benefit in male APP^NL-F mice.” Frontiers in Endocrinology 2026. Read more ›

Coassolo, L., et al. “Prohormone cleavage prediction uncovers a non-incretin anti-obesity peptide.” Nature 2025; 641(8061): 192–201. Read more ›

Abdelhameed, A. M., et al. “Adiponectin Receptor Agonist AdipoRon Ameliorates the Metabolic Complications in a Hyperandrogenic Rat Model of PCOS.” Endocrinology 2026; 167(1): bqaf173. Read more ›

Tanwar, V. S., et al. “Single-Cell Multimodal Profiling Highlights Persistent Aortic Smooth Muscle Cell Changes in Diabetic Mice Despite Glycemic Control.” Arteriosclerosis, Thrombosis, and Vascular Biology 2026. Read more ›

Deng, Q., et al. “A multi-omics map of diabetic nephropathy reveals c-Jun as a driver of tubular injury and metabolic stress.” bioRxiv 2026. Read more ›

Amleh, A., et al. “Gestational Ketosis Compromises Nephron Endowment and Long-Term Kidney Function in Offspring.” Journal of the American Society of Nephrology 2026. Read more ›

Chen, M., et al. “Increased urinary albumin excretion but less damaged renal tubular structures in mice with genetically decreased elmo1 post ischemia/reperfusion injury.” The Innovation 2026. Read more ›

Tanwar, V. S., et al. “Single-Cell Multimodal Profiling Highlights Persistent Aortic Smooth Muscle Cell Changes in Diabetic Mice Despite Glycemic Control.” Arteriosclerosis, Thrombosis, and Vascular Biology 2026. Read more ›

Tuncer, E., et al. “Epstein Barr virus antigen-induced autoantibodies against complement C1q exacerbate renal disease in lupus-prone mice.” Frontiers in Immunology 2026; 17. Read more ›

Xiang, L., et al. “Peptide Amphiphiles Hitchhike on Endogenous Biomolecules for Enhanced Cancer Imaging and Therapy.” Advanced Materials 2026. Read more ›

Lattibeaudiere, K. G., et al. “Oleic Acid and Succinic Acid: A Potent Nutritional Supplement in Improving Hepatic Glycaemic Control in Type 2 Diabetic Sprague–Dawley Rats.” Advances in Pharmacological and Pharmaceutical Sciences 2024; 2024: 5556722. Read more ›

Vega, R. B., et al. “Laroprovstat, the First Oral Small-Molecule PCSK9 Inhibitor for the Treatment of Hypercholesterolemia: Results From a Randomized, Single-Blind, Placebo-Controlled Study.” Circulation 2026. Read more ›

Zheng, Z., et al. “ARD-101, a Gut-Restricted TAS2R Agonist, Reduces Hunger in Adults and Promotes Weight Loss in DIO Mice With DPP-4 Inhibition.” Molecular Metabolism 2026. Read more ›

Mazitova, A. M., et al. “IL-17RC Signaling Connects Intestinal Microbiota and Neuroimmune Interactions in Atherosclerosis.” bioRxiv 2026. Read more ›

Meda Venkata, S. P., et al. “The Impact of Obesity on Diabetes Onset and Neovascularization in Mouse Models of Metabolic Stress.” International Journal of Molecular Sciences 2024; 25(2): 1214. Read more ›

Prasad, R., et al. “Sustained ACE2 Expression by Probiotic Improves Integrity of Intestinal Lymphatics and Retinopathy in Type 1 Diabetic Model.” Journal of Clinical Medicine 2023; 12(5): 1771. Read more ›

Abdelwahed, K. S., et al. “Pseurotin A Validation as a Metastatic Castration-Resistant Prostate Cancer Recurrence-Suppressing Lead via PCSK9-LDLR Axis Modulation.” Marine Drugs 2023; 21(4): 215. Read more ›

Trinder, M., et al. “Inhibition of Cholesteryl Ester Transfer Protein Preserves High-Density Lipoprotein Cholesterol and Improves Survival in Sepsis.” Circulation 2021; 143(9): 921–934. Read more ›

Trajberg, M. S., et al. “Dysregulation of Metabolic Pathways by Carnitine Palmitoyl-Transferase 1 Plays a Key Role in Central Nervous System Disorders: Experimental Evidence Based on…” Scientific Reports 2020. Read more ›

Alsirhani, A. M., Alzahrani, O. R., et al. “Beta-Caryophyllene Mitigates High Fat Diet-Induced Testicular Dysfunctions by Targeting JNK/ERK-1 and JAK-1/STAT-3 Pathways in Rats.” Scientific Reports 2026. Read more ›

Yu, H., et al. “Exploring the Antioxidant and Anti-Inflammatory Therapeutic Potential of Homoplantaginin, a Flavonoid Glycoside, in Ameliorating Gestational Diabetes Mellitus: In Vivo…” 3 Biotech 2026. Read more ›

Lattibeaudiere, K. G., et al. “Oleic Acid and Succinic Acid: A Potent Nutritional Supplement in Improving Hepatic Glycaemic Control in Type 2 Diabetic Sprague–Dawley Rats.” Advances in Pharmacological and Pharmaceutical Sciences 2024; 2024: 5556722. Read more ›

Eltohamy, E. A., et al. “Molecular and Genotoxic Effects of Sildenafil Citrate and Tramadol on Testis and Sperm Quality in Rat Males: Role of Apoptosis.” Journal of Agricultural Chemistry and Biotechnology 2023; 14(9): 109–116. Read more ›

Zhang, F., et al. “Quercetin Modulates AMPK/SIRT1/NF-κB Signaling to Inhibit Inflammatory/Oxidative Stress Responses in Diabetic High Fat Diet-Induced Atherosclerosis in the Rat Carotid Artery.” Experimental and Therapeutic Medicine 2020. Read more ›

Meda Venkata, S. P., et al. “The Impact of Obesity on Diabetes Onset and Neovascularization in Mouse Models of Metabolic Stress.” International Journal of Molecular Sciences 2024; 25(2): 1214. Read more ›

Prasad, R., et al. “Sustained ACE2 Expression by Probiotic Improves Integrity of Intestinal Lymphatics and Retinopathy in Type 1 Diabetic Model.” Journal of Clinical Medicine 2023; 12(5): 1771. Read more ›

Trinder, M., et al. “Inhibition of Cholesteryl Ester Transfer Protein Preserves High-Density Lipoprotein Cholesterol and Improves Survival in Sepsis.” Circulation 2021; 143(9): 921–934. Read more ›

Trajberg, M. S., et al. “Dysregulation of Metabolic Pathways by Carnitine Palmitoyl-Transferase 1 Plays a Key Role in Central Nervous System Disorders: Experimental Evidence Based on…” Scientific Reports 2020. Read more ›

Alsirhani, A. M., Alzahrani, O. R., et al. “Beta-Caryophyllene Mitigates High Fat Diet-Induced Testicular Dysfunctions by Targeting JNK/ERK-1 and JAK-1/STAT-3 Pathways in Rats.” Scientific Reports 2026. Read more ›

Yu, H., et al. “Exploring the Antioxidant and Anti-Inflammatory Therapeutic Potential of Homoplantaginin, a Flavonoid Glycoside, in Ameliorating Gestational Diabetes Mellitus: In Vivo…” 3 Biotech 2026. Read more ›

Lattibeaudiere, K. G., et al. “Oleic Acid and Succinic Acid: A Potent Nutritional Supplement in Improving Hepatic Glycaemic Control in Type 2 Diabetic Sprague–Dawley Rats.” Advances in Pharmacological and Pharmaceutical Sciences 2024; 2024: 5556722. Read more ›

Zhang, F., et al. “Quercetin Modulates AMPK/SIRT1/NF-κB Signaling to Inhibit Inflammatory/Oxidative Stress Responses in Diabetic High Fat Diet-Induced Atherosclerosis in the Rat Carotid Artery.” Experimental and Therapeutic Medicine 2020. Read more ›

Nan, J., et al. “Single-cell perturbations decipher ribosomal stress-surveillance regulators in type 2 diabetes.” Nature Metabolism 2026; 8: 139–158. Read more ›

Widener, A. E., et al. “β-cell function in preclinical diabetes models.” bioRxiv 2025. Read more ›

Chang, R. C., et al. “Heritable changes in chromatin contacts associated with transgenerational susceptibility to diet-induced insulin dysregulation and obesity.” Nature Communications 2026; 17: 2662. Read more ›

Duan, S., et al. “Hedgehog signaling drives glial cell plasticity and oncogenic reprogramming in gastroenteropancreatic neuroendocrine neoplasms.” Molecular Cancer 2026; 25: 85. Read more ›

Yu, H., et al. “Exploring the Antioxidant and Anti-Inflammatory Therapeutic Potential of Homoplantaginin, a Flavonoid Glycoside, in Ameliorating Gestational Diabetes Mellitus: In Vivo…” 3 Biotech 2026. Read more ›

Dong, X., et al. “Monoterpene A-Pinene Alleviates Diabetic Retinopathy in Rodent Model via Attenuating Hyperglycemia Induced VEGF Signaling.” Indian Journal of Pharmaceutical Sciences 2026. Read more ›

Ayachi, C., et al. “Harnessing Gut Endocrine Cell Plasticity to Restore Insulin Production.” Cells 2026; 15(6): 544. Read more ›

Lee, E., et al. “Effects of Daily Saskatoon Berry Supplementation on Cardiometabolic Health, Gut Microbiota, and Short-Chain Fatty Acids in Healthy Adults.” International Journal of Molecular Sciences 2026. Read more ›

Amleh, A., et al. “Gestational Ketosis Compromises Nephron Endowment and Long-Term Kidney Function in Offspring.” Journal of the American Society of Nephrology 2026. Read more ›